Published: Feb 04, 2021
SAN DIEGO, Feb. 04, 2021 (GLOBE NEWSWIRE) Crinetics Pharmaceuticals Inc.. (Nasdaq: CRNX), a clinical stage pharmaceutical company focused on the discovery, development, and commercialization of novel therapeutics for rare endocrine diseases and endocrine-related tumors, today announced that CRN04894, the company’s lead adrenocorticotropic hormone (ACTH) antagonist for the treatment of diseases associated with excess ACTH such as Cushing’s disease and congenital adrenal hyperplasia (CAH), has advanced into the clinic. Based on encouraging preclinical results, Crinetics has initiated a double-blind, randomized, placebo-controlled Phase 1 study of this orally administered, nonpeptide small molecule drug candidate in healthy volunteers. This study will assess the safety and tolerability of single and multiple doses of CRN04894 and will measure the effect of CRN04894 on suppression of cortisol, cortisol precursors, and adrenal androgens following exogen
U.S. to start distributing coronavirus vaccines directly to pharmacies Erin Cunningham, Paul Schemm, Lateshia Beachum, Hannah Knowles
What the Biden administration has said about vaccination goals
Replay Video UP NEXT The Biden administration said Tuesday it will start distributing limited supplies of vaccines directly to retail pharmacies beginning Feb. 11, in effort to make it faster and easier for people to get inoculated. These doses are separate from those allocated to states. Jeff Zients, Biden’s coronavirus coordinator, cautioned that supply constraints will limit the early availability of shots in drugstores. He said the administration wanted to target supplies to pharmacies serving “socially vulnerable communities.”
The Washington Post
February 1, 2021
Soon after Marc Wilson gets his second dose of coronavirus vaccine, he plans to resume one of his pre-pandemic joys: swimming laps with his friends. But most other activities – including volunteering at a food pantry and homeless shelter – will be off-limits until the outbreak is curbed and scientists know more about the threat of emerging variants.
“I can definitely broaden the things I do, but I still have to be quite cautious,” said Wilson, 70, a retired accountant in Norman, Okla., who has diabetes and other health problems. “When your doctor tells you, ‘If you get covid, you’re dead,’ that gets your attention real good.”
Manycoronavirus vaccine recipients wonder: What can I safely do?
After being vaccinated, Marc Wilson, 70, a retired accountant in Norman, Okla., plans to go back to some activities but not others. must credit: Photo for The Washington Post by Nick Oxford
Published February 01. 2021 4:28PM | Updated February 01. 2021 9:32PM
Laurie McGinley and Lenny Bernstein, The Washington Post
Soon after Marc Wilson gets his second dose of coronavirus vaccine, he plans to resume one of his pre-pandemic joys: swimming laps with his friends. But most other activities including volunteering at a food pantry and homeless shelter will be off-limits until the outbreak is curbed and scientists know more about the threat of emerging variants.