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IMAGE: Image of the SARS-CoV-2 spike in the active position. Dark blue glycans shield the spike from the immune system, participate in activation, and stabilize the active form. The receptor binding. view more
Credit: Image credit: Lorenzo Casalino, Amaro Lab, UCSD.
ROCKVILLE, MD - One thing that makes SARS-CoV-2, the virus that causes COVID-19, elusive to the immune system is that it is covered in sugars called glycans. Once SARS-CoV-2 infects someone s body, it becomes covered in that person s unique glycans, making it difficult for the immune system to recognize the virus as something it needs to fight. Those glycans also play an important role in activating the virus. Terra Sztain-Pedone, a graduate student, and colleagues in the labs of Rommie Amaro at the University of California, San Diego and Lillian Chong at the University of Pittsburgh, studied exactly how the glycans activate SARS-CoV-2. Sztain-Pedone will present the research on Thursday, February 2
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Feb. 25, 2021 - A new paper published online in the
Annals of the American Thoracic Society provides a roadmap that critical care clinicians professional societies can use to address burnout. While strongly needed prior to the COVID-19 pandemic, the roadmap has taken on even greater urgency due to reports of increasing pandemic-related burnout.
In Professional Societies Role in Addressing Member Burnout and Promoting Well-Being, Seppo T. Rinne, MD, PhD, of The Pulmonary Center, Boston University School of Medicine, and co-authors from a task force created by the Critical Care Societies Collaborative (CCSC) describe a rigorous process they used to document 17 major professional societies efforts to address burnout among health care professionals working in critical care, such as ICU physicians, physician assistants and nurses. The task force explored perspectives on the role of these societies to address burnout and developed a roadmap that the so
The study, published today in the
Lancet Regional Health by researchers from King s College London and the NIHR Guy s and St Thomas Biomedical Research Centre and supported by Impact on Urban Health, examined the prevalence of multimorbidity - two or more long-term diseases at once - and identified key relationships between diseases.
Researchers analysed electronic health records from participants aged 18 and over between April 2005 and May 2020 in one London borough. The borough has a deprived, multi-ethnic and youthful population.
Research showed multimorbidity is more common among women and Black ethnic minority groups. An estimated 21% of the population had multimorbidity and the number of conditions increased progressively with age, with people aged 80 and above having a median of four conditions.