The 30-share BSE index was trading 189.52 points or 0.37 per cent lower at 51,233.36 in initial deals, and the broader NSE Nifty fell 43.20 points or 0.28 per cent to 15,392.45.
While the Covid-19 situation is improving in India, other Asian countries are witnessing a rise in infections. This might impact sentiments for Asian markets in general, said an analyst.
The 30-share BSE index was trading 306.57 points or 0.60 per cent higher at 51,421.79, and the broader NSE Nifty surged 101.15 points or 0.66 per cent to 15,439.
Equities in other Asian markets cheered in the early session in line with global markets as strong US economic data solidified hopes of continuing recovery.