Photo Credit: Ron Waksman/Medstar Washington Hospital Center
The BASILICA procedure, which involves the intentional laceration of a preexisting aortic leaflet prior to TAVI in order to prevent coronary obstruction, can be safely performed in the vast majority of patients, according to new data from an international registry.
Among 214 patients undergoing BASILICA at 25 centers, the rate of death at 30 days was 2.8%, as was the rate of stroke, and just one patient (0.5%) had a disabling stroke.
Senior investigator Ron Waksman, MD (MedStar Washington Hospital Center, Washington, DC), said BASILICA offers a “unique solution” to patients at high risk for coronary obstruction with TAVI, one that isn’t associated with increased cost. “We wanted to prove that BASILICA was safe, number one, and feasible, number two, and effective,” Waksman told TCTMD.
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Registry data suggested that valve leaflet laceration helped protect patients at risk of coronary artery obstruction during transcatheter aortic valve replacement (TAVR).
Safety of the electrosurgical technique, known as Bioprosthetic or native Aortic Scallop Intentional Laceration to prevent Iatrogenic Coronary Artery obstruction (BASILICA), was reflected in the 3.4% rate of death or disabling stroke at 30 days among 214 patients.
Incidence was 2.8% for mortality, 2.8% for stroke, and 0.5% for disabling stroke, according to Ron Waksman, MD, of MedStar Washington Hospital Center, D.C., and colleagues, reporting in This is comparable to outcomes in patients undergoing TAVR who are not specifically at risk of coronary artery obstruction, the authors noted in their manuscript, presented simultaneously during the virtual Cardiovascular Research Technologies conference on Saturday.
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