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SUZHOU, China, June 1, 2021 /PRNewswire/ Transcenta Holding Limited ( Transcenta ), a global biotherapeutics company with fully-integrated capabilities in discovery, development and manufacturing of antibody-based therapeutics, announced completion of first patient dosing in PET-CT imaging study of radionuclide-labeled CLDN18.2 antibody.
The study was led by Professor Lin Shen and Dr. Hua Zhu, from Beijing Cancer Hospital, the objective of the study is to construct a non-invasive approach of
124I-18B10 PET-CT to detect the CLDN18.2 expression of tumor lesions in patients with gastrointestinal and other solid tumors, and to identify patients benefited from CLDN18.2 targeting treatment. The current preclinical findings showed that the antibody probe has high specificity to CLDN18.2 and it was specifically enriched in CLDN18.2 positive tumor site in tumor-bearing mice rather than normal tissues. The results of this study were presented in the
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Immunotherapy techniques developed in oncology to combat cancerous cells have great potential for fighting viruses. A research team from the University Hospitals of Geneva (HUG) and the University of Geneva (UNIGE), in Switzerland, in collaboration with MaxiVAX, a spinoff of both institutions, developed an innovative technology called “cell encapsulation”. Originally designed to stimulate immunity to fight cancer, the COVID-19 pandemic motivated the scientists to broaden the scope of their technology to test its effectiveness against viruses. The first results of a pre-clinical study are very encouraging and can be discovered in the journal Vaccines.
The immune system is able to identify cancer cells and fight them, just as it does against a viral or bacterial pathogen. Researchers therefore rely on this to develop vaccines against cancer. “To develop an effective vaccine, two elements are needed: a target recognized by the immune system, such as cells, proteins, DNA or
A team from the UNIGE and the HUG has developed a new and effective anti-viral vaccination technique based on the cell encapsulation. The cargo capsule.