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Clinical study identifies genetic changes in head-neck cancer, association with immunotherapy resistance

Clinical study identifies genetic changes in head-neck cancer, association with immunotherapy resistance Clinical study identifies genetic changes in head-neck cancer, association with immunotherapy resistance Last Updated: Tue, Apr 27th, 2021, 10:20:08hrs Washington [US], April 27 (ANI): A multi-institutional team of researchers has identified both the genetic abnormalities that drive pre-cancer cells into becoming an invasive type of head and neck cancer and patients who are least likely to respond to immunotherapy. Through a series of surprises, we followed clues that focused more and more tightly on specific genetic imbalances and their role in the effects of specific immune components in tumour development, said co-principal investigator Webster Cavenee, PhD, Distinguished Professor Emeritus at the University of California San Diego School of Medicine.

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Louisiana Mesothelioma Victims Center Appeals to the Family of an Individual in Louisiana with Mesothelioma to Call Attorney Erik Karst of Karst von Oiste About Compensation-Do Not Rely on a Local Car Accident Attorney
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Genetic changes in head and neck cancer, immunotherapy resistance identified

 E-Mail A multi-institutional team of researchers has identified both the genetic abnormalities that drive pre-cancer cells into becoming an invasive type of head and neck cancer and patients who are least likely to respond to immunotherapy. Through a series of surprises, we followed clues that focused more and more tightly on specific genetic imbalances and their role in the effects of specific immune components in tumor development, said co-principal investigator Webster Cavenee, PhD, Distinguished Professor Emeritus at University of California San Diego School of Medicine. The genetic abnormalities we identified drive changes in the immune cell composition of the tumors that, in turn, dictates responsiveness to standard of care immune checkpoint inhibitors.

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