Clinical data quashes experimental Covid-19 therapies from Brii, Vir & Apellis
Antibody therapies from Brii Biosciences and Vir Biotechnology failed to show sufficient efficacy to advance to the next stage of an NIH-sponsored Covid-19 clinical trial. Apellis Pharmaceuticals and Durect also stopped work on experimental Covid treatments.
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Drug developers are still trying different approaches to treating Covid-19 but clinical trial results this week halted several potential therapies, including two that are part of a National Institutes of Health program evaluating treatments for hospitalized patients.
The NIH’s Accelerating Covid-19 Therapeutic Interventions and Vaccines (ACTIV) program launched to speed up the development and testing of treatments and vaccines. The study uses an adaptive two-stage design for the Phase 3 test. A treatment that demonstrates safety in stage 1 can proceed to stage 2, following review by an independent board.
Swelling after COVID-19 shots may cause cancer false alarms
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Swelling after COVID-19 shots may cause cancer false alarms
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