Identifying SARS-CoV-2 epitopes targeted by current vaccination could help improve future vaccines
Researchers in the United States have identified antibody-inducing epitopes of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in individuals vaccinated against coronavirus disease 2019 (COVID-19) that could be used for future diagnostics, therapeutics, and vaccine design.
Using an approach called reverse vaccinology, the team identified distinct amino acid motifs and epitopes of the SARS-CoV-2 spike protein that elicit specific immunoglobulin IgG antibody responses that have previously been associated with neutralization of the virus.
The spike protein is the main structure SARS-CoV-2 uses to infect cells and the primary target of neutralizing antibodies following vaccination or natural infection.
Sunscreen With Leukemia-Causing Benzene Is Latest Summer Worry bnnbloomberg.ca - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from bnnbloomberg.ca Daily Mail and Mail on Sunday newspapers.
A massive study of genetic and health records of 1.2 million people from four separate data banks has identified 178 gene variants linked to major depression.
E-Mail
IMAGE: Health science specialist Yasamin Azadzoi removes Million Veteran Program samples from a cryotank at the Boston MVP facility. view more
Credit: Frank Curran
In the largest genetic analysis of depression to date, Veterans Affairs researchers identified many new gene variants that increase the risk for depression. The groundbreaking study helps researchers better understand the biological basis of depression and could lead to better drug treatments.
The study involved genetic data on more than 300,000 participants of VA s Million Veteran Program (MVP), along with more than a million subjects from other biobanks, including 23andMe. With such a large participant pool, the researchers were able to spot trends in genetic risk of depression not previously known.
Was COVID created in a lab? Yale researcher calls for probe into origins of the virus
FacebookTwitterEmail
1of3
FILE - In this Feb. 2, 2021, file photo, a member of a World Health Organization team is seen wearing protective gear during a field visit to the Hubei Animal Disease Control and Prevention Center for another day of field visit in Wuhan in central China s Hubei province. A joint WHO-China study on the origins of COVID-19 says that transmission from bats to humans through another animal is the most likely scenario and that a lab leak is “extremely unlikely, according to a draft copy obtained by The Associated Press.Ng Han Guan / Associated PressShow MoreShow Less