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AGA recommends intragastric balloons as an additional weight loss strategy for obese patients

 E-Mail Bethesda, MD (April 6, 2021) Obesity is a global pandemic, affecting about 40% of adults in the United States. There is an enormous unmet need for an effective weight-loss solution. After a detailed review of available literature, the American Gastroenterological Association (AGA) has released new clinical guidelines recommending the use of intragastric balloons (IGB) for patients with obesity who have not been able to lose weight with traditional weight-loss strategies. This treatment is most successful with accompanying therapy, such as lifestyle modifications and pharmacological agents, and can be used in a sequential manner or along with bariatric surgery. These guidelines are published in

For the Best Melanoma Prognosis, Location Matters

Apr 2, 2021 Patients who receive Mohs micrographic surgery fare better at academic/top volume facilities, retrospective analysis suggests Where a patient with early melanoma gets treated appeared to affect prognosis, a retrospective analysis suggested, as those who received Mohs micrographic surgery (MMS) at either an academic or a top volume facility had better long-term survival outcomes than those who had the same procedure done at a nonacademic or a low volume facility. In a cohort of 4062 patients with nonmetastatic, T1a-T2a melanoma, those who underwent surgery at an academic facility had a nearly 30% lower risk of death at a hazard ratio (HR) of 0.73 (95% CI, 0.59-0.89) compared to patients who underwent surgery at a nonacademic facility, senior author Michael Girardi, MD, Yale University School of Medicine, New Haven, Connecticut, and colleagues reported in

Why you should never eat potato chips with Diet Coke, according to brain science

Follow Apr. 1, 2021 Everyone is familiar with the experiment carried out near the turn of the 19th century by Ivan Pavlov, the Russian physiologist. It’s become synonymous with conditioning, or an involuntary response to a stimulus. Pavlov fed dogs and measured their salivation. He repeated this time after time, and observed that the sounds that preceded the food distribution began themselves to cause the dogs to salivate. That happened even when the bell he rang wasn’t followed by food. Nearly a hundred years later, the Canadian scientist Harvey Weingarten conducted a similar experiment. He used rats instead of dogs, but he also sounded a tone while feeding them. The results were similar: the rats associated the sound of the bell with food. But then Weingarten expanded the experiment: He gave the rats a meal when they weren’t hungry. The rats saw the food but ignored it completely. Until he rang the bell, that is. Now, Weingarten discovered, the rats, which had only a short

Inozyme Pharma Expands its Scientific Advisory Board

Press release content from Globe Newswire. The AP news staff was not involved in its creation. Inozyme Pharma Expands its Scientific Advisory Board Inozyme Pharma Inc.April 1, 2021 GMT BOSTON, April 01, 2021 (GLOBE NEWSWIRE) Inozyme Pharma, Inc., a rare disease biopharmaceutical company developing novel therapeutics for the treatment of disorders of abnormal mineralization, announced today changes to its scientific advisory board (SAB), including the addition of three leading key opinion leaders with specific expertise in the company’s lead indications: W Charles O’Neill IV, M.D., Director of the Ultrasonography Program in the Renal Division at Emory University School of Medicine

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