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 E-Mail Researchers at the University of Maryland School of Medicine published one of the most comprehensive analyses of how genes get expressed during infection (known as a transcriptome). The analyses include three different strains of the bacteria Streptococcus pneumoniae, which causes pneumonia, meningitis and middle-ear infections. It also includes analyses of the lungs and four other organs in an animal model where the bacteria resides, multiplies and takes hold in the body. Their findings were published today in the Proceedings of the National Academy of Sciences. Our new analysis provides valuable new information about the animal host and pathogen interactions that take place during pneumococcal infections, said study principal investigator Hervé Tettelin, PhD, a Professor of Microbiology and Immunology, and scientist at the Institute for Genome Sciences in the University of Maryland School of Medicine. It could ultimately help researchers develop new treatments for

Akikok bowersE albert reeceAdonis dmelloCenters for diseaseMerck investigator studies programNational institute of allergyNational institutes of healthInstitute for genome sciencesUniversity of alabama at birminghamProceedings of the national academy sciencesUniversity of maryland school medicineYale university school of medicineMaryland schoolNational academyGenome sciencesDisease control