Researchers find new method for safe and effective delivery of medicines to the lungs
Investigators at Rutgers Cancer Institute of New Jersey and Rutgers New Jersey Medical School recently identified a new method for safe and effective delivery of medicines to the lungs that can be used for multiple clinical applications, potentially including aerosol vaccination. The results of the study will be published online ahead of print in the December issue of
Med (10.1016/j.medj.2020.10.005).
Targeted pulmonary delivery may have many conceptual advantages over other routes of vaccine administration and therapeutics, particularly for certain respiratory infections (including but not limited to SARS-CoV-2) because they arrive directly at the site of the infection.
Published: Dec 10, 2020
NEW YORK, Dec. 10, 2020 /PRNewswire/ PhageNova Bio, Inc. ( PhageNova ) is pleased to announce the publication of data generated through a sponsored research agreement with Rutgers, The State University of New Jersey. The
Med (a
Cell Press publication) article, entitled
Targeted Phage Display-Based Pulmonary Vaccination in Mice and Non-human Primates, describes a new method for safe and effective pulmonary delivery of therapeutics, including an aerosol vaccination strategy which is being developed to address the current SARS-CoV-2 pandemic. Our targeted method of pulmonary delivery is the initial step towards the development of aerosol phage-based vaccines for human applications against multiple diseases, says Renata Pasqualini, PhD, co-senior study author, Founder and Chief Scientific Officer of PhageNova, and Chief of the Division of Cancer Biology, Department of Radiation Oncology at Rutgers Cancer Institute and Rutgers New Jersey Medic
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IMAGE: Dr. Dobryakova is research scientist in the Center for Traumatic Brain Injury Research at Kessler Foundation. view more
Credit: Kessler Foundation
East Hanover, NJ, December 10, 2020. Researchers at Montclair State University and Kessler Foundation have received funding totaling $651,997 from the National Multiple Sclerosis Society to measure memory-related abilities in individuals with and without multiple sclerosis (MS) for clues to how such cognitive processes are altered by MS. Joshua Sandry, PhD, assistant professor of psychology at Montclair State and Ekaterina Dobryakova, PhD, research scientist in the Center for Traumatic Brain Injury Research at Kessler Foundation, collaborate on the 4-year study, titled Neuroimaging of Hippocampally Mediated Memory Dysfunction in Multiple Sclerosis.
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