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NIH funds eight studies to uncover risk factors for COVID-19-related inflammatory syndrome in children

Share this article Share this article BETHESDA, Maryland., Dec. 28, 2020 /PRNewswire-HISPANIC PR WIRE/  The National Institutes of Health has awarded eight research grants to develop approaches for identifying children at high risk for Multisystem Inflammatory Syndrome in Children (MIS-C), a rare and severe after-effect of COVID-19 or exposure to the virus that causes it. Up to $20 million will be provided for the projects over four years, pending the availability of funds. These awards underscore NIH s commitment to identifying children at risk for MIS-C, which will inform development of interventions to improve their health outcomes, said Diana Bianchi, M.D., director of NIH s

Study assesses link between secondary bloodstream infection and severe COVID-19

Study assesses link between secondary bloodstream infection and severe COVID-19 People with severe COVID-19 and a secondary blood infection were significantly sicker upon hospital admission, had longer hospital stays and poorer outcomes, according to a Rutgers study. The study, published in the journal Clinical Infectious Diseases, is the first to assess the microbiology, risk factors and outcomes in hospitalized patients with severe COVID-19 and secondary bloodstream infections. The researchers looked at 375 patients diagnosed with severe COVID-19 from March to May 2020. Of that group, they sampled 128 cases who had secondary bloodstream infections, 92 percent of which were bacterial infections. These patients were more likely to have altered mental status, lower percent oxygen saturation, septic shock and to be admitted to the intensive care unit compared to those without bloodstream infections.

Secondary blood infection linked to worse COVID-19 outcomes

The study, published in the journal Clinical Infectious Diseases, is the first to assess the microbiology, risk factors, and outcomes in hospitalized patients with severe COVID-19 and secondary bloodstream infections. The researchers looked at 375 patients diagnosed with severe COVID-19 from March to May 2020. Of that group, they sampled 128 cases who had secondary bloodstream infections, 92% of which were bacterial infections. “These patients were more likely to have altered mental status, lower percent oxygen saturation, septic shock, and to be admitted to the intensive care unit compared to those without bloodstream infections,” says co-lead author Pinki Bhatt, an assistant professor at Rutgers Robert Wood Johnson Medical School’s Division of Allergy, Immunology, and Infectious Disease.

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