Study could guide future treatment of multisystem inflammatory syndrome in children
Children and adolescents with multisystem inflammatory syndrome in children (MIS-C) who are treated initially with intravenous immune globulin (IVIG) and glucocorticoids have reduced risk for serious short-term outcomes, including cardiovascular dysfunction, than those who receive an initial treatment of IVIG alone, a new study finds.
MIS-C is a rare but serious and sometimes fatal condition associated with COVID-19, in which different body organs or systems become inflamed, including the heart, lungs, kidneys, brain, skin, eyes, or gastrointestinal system. It can occur weeks after having COVID-19 and even if the child or caregivers did not know the child had been infected.
New study may offer treatment guidance for MIS-C
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Even those who are unfamiliar with the benefits of probiotics are likely aware of where and how they re used, such as in yogurt cultures and dietary supplements.
It is those who don t include probiotics in their daily routines who Rutgers University is now seeking for a 54-person clinical research study to determine if the live bacteria can boost immune defense, including antibody levels, against COVID-19.
To be otherwise eligible for the study, participants must have tested positive for COVID at least four months ago, and they cannot yet have been vaccinated.
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Daniel Horton, assistant professor of pediatrics and epidemiology at Rutgers Robert Wood Johnson Medical School and lead investigator for the study, said exposure to the virus and a reliance on natural antibodies are the keys to judging the probiotics potential effectiveness.
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