Composition and structure of nasopharyngeal microbiome relate to COVID-19 disease severity
Viral infections are associated with changes in the upper respiratory tract/nasopharyngeal (NP) microbiome. In addition, many studies hypothesize the possibilities of ‘super infections’ due to suppressed immunity during a viral onslaught.
Virulent pathogens can be promoted by microbiota, but commensal microbiota can also suppress the spread of viruses. It has been shown that these interactions affect clinical outcomes.
How does the ongoing COVID-19 (coronavirus disease 2019) pandemic, caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), affect the bacterial microbiome?
In a recent study led by Dr. Amy K Feehan, researchers hypothesized that the COVID-19 status would be associated with a shift in the NP microbiome, especially in hospitalized patients. The results from this study support the dynamic and significant changes to the microbiome in the NP space, especially w
Rapid quantification of SARS-CoV-2 Spike-specific T cells by direct peptide stimulation of whole peripheral blood
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Zinc-embedded polyamides inactivate SARS-CoV-2 and influenza A
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SARS-CoV-2 inhibited by pyrimidine biosynthesis inhibitors in conjunction with nucleoside analogs
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An affordable, scalable and highly sensitive virus-genome-based testing approach
COVID-19 (coronavirus 2019), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is continuing to cause morbidity and mortality, despite ongoing mitigation strategies and vaccination efforts. Attempts by most countries to combat COVID-19 shave relied on social distancing, lockdowns, limited testing, contact tracing, and vaccine rollouts, all of which are now helping to fight the pandemic.
Aiming to reduce human suffering, economic costs, and restrictions on personal freedom caused by COVID-19 to a minimum, researchers from Germany and Austria proposed an alternative method - efficient population-based genome-based testing.
They demonstrated an affordable, scalable, and highly sensitive virus genome-based testing approach developed as part of the Human Genome Project.