Three of the trials did not have study acronyms (only trial registration numbers) and ILBS-COVID-02 and PLACID did not have expansions in the original publications. ConCOVID indicates Convalescent Plasma as Therapy for Covid-19 Severe SARS-CoV-2 Disease; ConPlas-19, Convalescent Plasma Therapy vs SOC for the Treatment of COVID-19 in Hospitalized Patients; NA, not available; PICP19, Passive Immunization With Convalescent Plasma in Severe COVID-19 Disease; PlasmAr, Convalescent Plasma and Placebo for the Treatment of COVID-19 Severe Pneumonia; RECOVERY, Randomized Evaluation of COVID-19 Therapy.
aThere was no detailed information reported regarding (1) the randomization process or (2) the concealment of randomized assignment.
bThere was no detailed information reported regarding (1) the randomization process, (2) the concealment of randomized assignment, (3) the flow of patients through the trial, and (4) possible deviations from the intended interventions due to the open-label setti
Examining the Ugandan health system’s readiness to deliver rheumatic heart disease-related services
Emma Ndagire, Roles Formal analysis, Writing – original draft, Writing – review & editing
Affiliations Uganda Heart Institute, Kampala, Uganda, Children’s National Hospital, Division of Cardiology, Washington, District of Columbia, United States of America ⨯
Yoshito Kawakatsu,
Affiliation Department of Global Health, University of Washington, Seattle, Washington, United States of America
Affiliation Uganda Heart Institute, Kampala, Uganda
Affiliation Uganda Heart Institute, Kampala, Uganda Roles Formal analysis, Writing – review & editing
Affiliation Children’s National Hospital, Division of Cardiology, Washington, District of Columbia, United States of America ⨯
Jafesi Pulle,
Affiliation Uganda Heart Institute, Kampala, Uganda
Science for just $15 USD.
Abstract
The biomechanics underlying the predatory strike of dragonfly larvae is not yet understood. Dragonfly larvae are aquatic ambush predators, capturing their prey with a strongly modified extensible mouthpart. The current theory of hydraulic pressure being the driving force of the predatory strike can be refuted by our manipulation experiments and reinterpretation of former studies. Here, we report evidence for an independently loaded synchronized dual-catapult system. To power the ballistic movement of a single specialized mouthpart, two independently loaded springs simultaneously release and actuate two separate joints in a kinematic chain. Energy for the movement is stored by straining an elastic structure at each joint and, possibly, the surrounding cuticle, which is preloaded by muscle contraction. As a proof of concept, we developed a bioinspired robotic model resembling the morphology and functional principle of the extensible mouthpart. Under
Congenital syphilis in Argentina: Experience in a pediatric hospital
Luciana Noemí Garcia , Roles Project administration, Visualization, Writing – original draft Roles Data curation, Formal analysis, Investigation, Writing – original draft
Affiliation Servicio Parasitología- Chagas, Hospital de Niños Ricardo Gutierrez, Capital Federal, Buenos Aires, Argentina ⨯
Samanta Moroni,
Affiliation Servicio Parasitología- Chagas, Hospital de Niños Ricardo Gutierrez, Capital Federal, Buenos Aires, Argentina ⨯
Nicolas Falk, Roles Formal analysis, Methodology, Software
Affiliations Servicio Parasitología- Chagas, Hospital de Niños Ricardo Gutierrez, Capital Federal, Buenos Aires, Argentina, Instituto Multidisciplinario de Investigaciones en Patologías Pediátricas (IMIPP), CONICET, Buenos Aires, Argentina ⨯
Nicolás Gonzalez,
1Department of Oceanography and Fisheries, University of the Azores, Horta, Portugal
2Department of Biological Sciences and K.G. Jebsen Centre for Deep-Sea Research, University of Bergen, Bergen, Norway
Few studies have described the effects of physical disturbance and post-recovery of deep-sea benthic communities. Here, we explore the status of deep-sea sponge ground communities four years after being impacted by an experimental bottom trawl. The diversity and abundance of epibenthic megafauna of two distinct benthic communities in disturbed versus control areas were surveyed using a remotely operated vehicle on the Schulz Bank, Arctic Ocean. Four years after disturbance, megafaunal densities of the shallow (∼600 m depth) and deep (∼1,400 m depth) sites were significantly lower on the disturbed patches compared to the control areas. Multivariate analyses revealed a distinct separation between disturbed and control communities for both sites, with trawling causing 29–58% of t