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EU regulator backs AstraZeneca jab, but many still suspending use
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Experts who argue that the coronavirus vaccine developed by AstraZeneca and Oxford University is safe – and certainly safer than getting Covid-19 – circled their wagons on Tuesday, but not before more countries suspended the jab.
The European Medicines Agency (EMA) – which approved the vaccine in January – remains convinced of the safety of AstraZeneca’s product, the organization’s chief said on Tuesday.
“A situation like this is not unexpected,” executive director Emer Cooke said, referring to several cases of blood clots that had reportedly developed following an injection. “When you vaccinate millions of people, it’s inevitable that you have rare or serious incidences of illnesses that occur after vaccination.”
EU Medical Regulator Backs AstraZeneca Vaccine
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Ask Dr. Scott: Might the ‘nocebo effect’ undermine Covid vaccine?
Ask Dr. Scott: Dr. Scott T. Anderson
Most of us are familiar with the placebo effect. A pill containing no pharmaceutical agent, often used in a control group when testing a new drug, can lead to subjective improvement in well-being among people taking said product.
A similar effect is gaining currency in the medical literature: the “nocebo effect.” In this case, anticipation of side effects leads to adverse subjective feelings in a person taking a medication or even a placebo.
Nocebo effects were recently studied with respect to cholesterol-lowering agents, as summarized in Medical News & Perspectives by Anita Slomski. The public perception is that so-called “statin” drugs may cause debilitating muscle pains. A comparative trial, published in the New England Journal of Medicine, demonstrated that 90% of these adverse effects were due to the nocebo effect.