Study: US COVID infections may have been twice the number reported
Roughly 15.9 million asymptomatic US COVID-19 cases may have gone undetected as of Sep 30, 2020, which would double the cases reported to the Centers for Disease Control and Prevention (CDC) during that time, according to a research letter detailing a 6.6% nationwide SARS-CoV-2 seroprevalence rate.
The letter, written by Clinical Reference Laboratory scientists in Kansas and published today in
JAMA Network Open, describes a national convenience sample of 61,910 generally healthy adult life insurance applicants evaluated for the presence of SARS-CoV-2 antibodies in September.
Of the 61,910 participants, 4,094 (6.6%) had coronavirus antibodies, or were seropositive, indicating previous COVID-19 infection. Slightly more women than men were seropositive (6.9% vs 6.4%). Seroprevalence rates varied widely by state and ranged from 2.8% in participants older than 70 years to 9.8% in those younger than 30.
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