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The role of people infected with malaria without showing symptoms presents a hidden risk to efforts to control the disease after they were found to be responsible for most infections in mosquitoes, according to a study published in
The Lancet Infectious Diseases.
Researchers from the Infectious Diseases Research Collaboration (IDRC), London School of Hygiene & Tropical Medicine (LSHTM), Radboud university medical center and University of California, San Francisco, found asymptomatic children in the Uganda study were the biggest source of malaria parasites transmitted to mosquitoes. This could provide a new opportunity for control efforts by targeting this infectious reservoir.
Malaria presents a major health threat globally, with 94% of cases on the African continent alone, according to the WHO World Malaria Report 2020. The disease is passed to a human through the bite of an infected female
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Efforts to reduce the number of heart attacks and strokes are being stalled by weight gain and increasing diabetes prevalence, analysis of Scottish health data suggests.
But progress in further reducing cardiovascular disease has been hampered by increasing body mass index (BMI) and diabetes prevalence over the same period.
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The number of heart attacks in Scotland fell from 1069 per 100,000 people in 1990 to 276 per 100,000 people in 2014.
Ischaemic strokes, which are caused by a blood clot in the brain, fell from 608 per 100,000 people to 188 per 100,000 people over the same period.
The study found that 74 per cent of this fall in heart attacks and 68 per cent of the reduction in strokes could be accounted for by changes in risk factor prevalence.