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A study of 44,541 women has found that there appears to be no association between type 2 diabetes and developing breast cancer overall. This may be because most women in the study with type 2 diabetes were taking metformin, a medication widely used to treat type 2 diabetes, whose actions may help to reduce the risk of developing oestrogen positive (ER-positive) breast cancer.
ER-positive breast cancer (cancer that has receptors on cell surfaces for the hormone oestrogen) accounts for about 80% of breast cancer diagnosed in the USA. Associations uncovered in the study suggested that the link between type 2 diabetes and breast cancer varied by breast cancer subtype and was affected by the use of metformin to treat diabetes. The study is published in the leading cancer journal
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The results of a randomised clinical trial with the longest follow up to date show that metabolic surgery is more effective than medications and lifestyle interventions in the long-term control of severe type 2 diabetes.
The study, published today in
The Lancet, also shows that over one-third of surgically-treated patients remained diabetes-free throughout the 10-year period of the trial. This demonstrates, in the context of the most rigorous type of clinical investigation, that a cure for type 2 diabetes can be achieved.
Researchers from King s College London and the Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Rome, Italy report the 10-year outcomes of a trial that compared metabolic surgery with conventional medical and lifestyle interventions in patients with type 2 diabetes.
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IMAGE: Elizabeth Parks, PhD, professor of nutrition and exercise physiology at the University of Missouri School of Medicine view more
Credit: Justin Kelley
The NFL playoffs are underway, and fans are finding ways to simulate tailgating during the COVID-19 pandemic. Football watch parties are synonymous with eating fatty foods and drinking alcohol. Have you ever wondered what all of that eating and drinking does to your body?
Researchers from the University of Missouri School of Medicine simulated a tailgating situation with a small group of overweight but healthy men and examined the impact of the eating and drinking on their livers using blood tests and a liver scan. They discovered remarkably differing responses in the subjects.
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IMAGE: The researchers examined data from study participants of the EPIC-Potsdam study who developed type 2 diabetes during the follow-up of the study. Thus, an increase in risk for microvascular complications. view more
Credit: Source: DIfE
Successful weight loss is considered to be an integral part of the therapy for type 2 diabetes. Nevertheless, studies keep appearing that question the importance of losing weight. However, new data from a large-scale observational study carried out at DIfE in cooperation with the German Center for Diabetes Research (DZD) support the current recommendations of physicians. The findings, published in the journal
Diabetologia, suggest that obesity and weight gain can lead to vascular disorders, the leading cause of disease and death for people with type 2 diabetes.
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BOSTON While deaths related to heart disease have declined among older people, studies suggest that death rates among younger patients have remained stagnant or increased slightly. To understand what factors put younger individuals at higher risk of premature coronary heart disease (CHD), researchers from Brigham and Women s Hospital and the Mayo Clinic analyzed more than 50 risk factors in 28,024 women who participated in the decades-long Women s Health Study. Notably, women under 55 with type-2 diabetes had a tenfold greater risk of having CHD over the next two decades, with lipoprotein insulin resistance (LPIR) proving to be a strong, predictive biomarker as well. Findings are published in