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Uterine fibroids are a common cause of heavy menstrual bleeding and pain in women of reproductive age, especially among women of color. An estimated $34 billion in healthcare costs are associated with uterine fibroids in the United States alone each year, yet there are few treatment options other than surgery.
Now a University of Chicago Medicine researcher working with an international team of scientists has developed a daily oral combination therapy that is reliable, safe and effective for long-term treatment of uterine fibroids. This discovery is an important new tool that will be an important addition to the field, said Ayman Al-Hendy, MD, PhD, a professor of obstetrics and gynecology and lead author of the study, which was published February 17, 2021 in the
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IMAGE: Recently, Professor Gen-ichiro Arimura from Tokyo University of Science, Japan, encapsulated the research on the herbivory-sensing mechanism of plants through elicitors. Commenting of the immense value of these elicitors, Prof.. view more
Credit: Gen-ichiro Arimura, Tokyo University of Science
Nature has its way of maintaining balance. This statement rightly holds true for plants that are eaten by herbivores insects or even mammals. Interestingly, these plants do not just silently allow themselves to be consumed and destroyed; in fact, they have evolved a defense system to warn them of predator attacks and potentially even ward them off. The defense systems arise as a result of inner and outer cellular signaling in the plants, as well as ecological cues. Plants have developed several ways of sensing damage; a lot of these involve the sensing of various elicitor molecules produced by either the predator or the plants themselves and initiation of an SOS
B. infantis EVC001 on key health indicators specifically in pre-term infants. The work was conducted at two neonatal intensive care units (NICU) in Southern California. Neonatologists, neonatal nurses and other hospital-based clinical staff are acutely focused on affecting the factors that positively impact quality of care and length of stay among pre-term infants, said Dr. Karl Sylvester, Pediatric Surgeon, Stanford, California. This study provides compelling evidence that feeding
B. infantis EVC001 to preterm infants, along with human milk, yields meaningful reduction in gut dysbiosis, antibiotic resistant gene abundance and enteric inflammation - all leading health indicators that are linked to key health outcomes.
Ciliopathies are genetic disorders caused by defects in the structure and function of cilia, and present a wide range of clinical symptoms, leading to conditions such as micrognathia (an underdeveloped lower jaw that can impair feeding and breathing). Researchers have now discovered that ciliopathic micrognathia in an animal model results from abnormal skeletal differentiation and remodelling.