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What are Neutrophil Extracellular Traps (NETs)? The formation of neutrophil extracellular traps (NETs) from neutrophils can be induced by various microorganisms ranging from whole bacteria to fungi and protozoan parasites. In addition to their role in fighting infections, NETs have also emerged as a novel target for cancer therapy. Image Credit: Kateryna Kon / Shutterstock.com The role of neutrophils As the most abundant leukocyte, which can also be referred to as white blood cells (WBC), present within the blood of human beings, neutrophils are the first line of defense against invading pathogens. Neutrophils can employ several different mechanisms in their attack against microbes including phagocytosis, the generation of reactive oxygen species (ROS) and degranulation. Phagocytosis, for example, involves the engulfment and subsequent digestion of pathogens like bacteria or fungi by neutrophils.

United statesBenedette cuffariKateryna kon shutterstockAmerican society of clinical oncologyDrug administrationKateryna konAmerican societyClinical oncologyUnited states foodInfection microbiologyDel vecchioEmerging roleNeutrophil extracellular trapsTumor progressionTranslational medicineஒன்றுபட்டது மாநிலங்களில்