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Antibody cocktails effective against SARS-CoV-2 mutations

Antibody cocktails effective against SARS-CoV-2 variants Written by Timothy Huzar on March 11, 2021 — Fact checked by Mary Cooke, Ph.D. Numerous therapeutics have been developed to treat COVID-19. However, many are based on initial variants of SARS-CoV-2 and may be less effective against recent ones. In the present study, researchers have identified monoclonal antibody “cocktails” that are still effective against recent variants. All data and statistics are based on publicly available data at the time of publication. Some information may be out of date. for the most recent information on the COVID-19 pandemic. In laboratory tests, a team of researchers has analyzed the efficacy of a range of COVID-19 antibody-based therapeutics against the latest variants of SARS-CoV-2.

SARS-CoV-2 mAb cocktail effective against all known variants of virus

SARS-CoV-2 mAb cocktail effective against all known variants of virus 63 A monoclonal antibody (mAb) cocktail, that targets sites on the Spike protein other than the E484K residue, can neutralise SARS-CoV-2. A monoclonal antibody (mAb) cocktail to neutralise the COVID-19 virus developed at Vanderbilt University Medical Center (VUMC), US, is effective against all known strains, or variants, of the virus, according to researchers. The study was led by scientists at Washington University School of Medicine in St Louis, US.  In cell culture studies, the researchers determined the ability of mAbs, as well as antibodies isolated from the convalescent plasma of previously infected people, to neutralise highly transmissible variants of the SARS-CoV-2 virus that have arisen in the UK, South Africa, Brazil and elsewhere.

Study: Monoclonal antibody cocktail effective against all known COVID-19 variants

A monoclonal antibody "cocktail" developed at Vanderbilt University Medical Center (VUMC) to neutralize the COVID-19 virus is effective against all known strains, or variants, of the virus, according to a report published in the journal Nature Medicine.

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