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From the front lines to the lab: Maryland s military members were instrumental in stopping, preventing COVID s spread

It’s been a year since COVID-19 cases first appeared in the state and Anne Arundel County. Across Maryland, military units from the Maryland National Guard to the U.S. Army Medical Research and Development Command started responding to the health crisis, finding ways to support testing, treatment and, ultimately, vaccination.

Immunogenicity of the Ad26 COV2 S Vaccine for COVID-19 | Vaccination | JAMA

9. Chung  AW, Kumar  MP, Arnold  KB,  et al.  Dissecting polyclonal vaccine-induced humoral immunity against HIV using systems serology.  10. Walsh  EE, Frenck  RW  Jr, Falsey  AR,  et al.  Safety and immunogenicity of two RNA-based Covid-19 vaccine candidates.  11. Widge  AT, Rouphael  NG, Jackson  LA,  et al; mRNA-1273 Study Group.  Durability of responses after SARS-CoV-2 mRNA-1273 vaccination.  12. Anderson  EJ, Rouphael  NG, Widge  AT,  et al; mRNA-1273 Study Group.  Safety and immunogenicity of SARS-CoV-2 mRNA-1273 vaccine in older adults.  13. Jackson  LA, Anderson  EJ, Rouphael  NG,  et al; mRNA-1273 Study Group.  An mRNA vaccine against SARS-CoV-2: preliminary report.  14. Foleg

A call to arms

Science s COVID-19 reporting is supported by the Heising-Simons Foundation ILLUSTRATION: STEPHAN SCHMITZ/FOLIO ART In March 2020, as the scope of the COVID-19 pandemic was coming into view, Jen Nwankwo and colleagues turned a pair of artificial intelligence (AI) tools against SARS-CoV-2. One newly developed AI program, called SUEDE, digitally screens all known druglike compounds for likely activity against biomolecules thought to be involved in disease. The other, BAGEL, predicts how to build inhibitors to known targets. The two programs searched for compounds able to block human enzymes that play essential roles in enabling the virus to infect our cells. While SUEDE sifted through 14 billion compounds in just hours and spit out a hit, BAGEL made equally fast work of designing a lead. Nwankwo, CEO of a Massachusetts biotech startup called 1910 Genetics, asked a chemical company partner to synthesize the compounds. A week or so later, her team received the orders, added each compou

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