In a new study currently available on the bioRxiv preprint server, a group of US-based researchers developed a panel of neutralizing monoclonal antibodies against SARS-CoV-2 that can block viral attachment to cells – and pinpointed a specific one that can potently neutralize all tested variants of concern.
New preclinical research, published in Nature, suggests a new avenue for Alzheimer’s disease (AD) treatment, through restoring lymphatic flow in the brain
Impaired drainage also may play a role in Alzheimer’s in people
The drainage network in a mouse’s brain is outlined in blue and green, and dotted with clumps of the Alzheimer’s protein amyloid beta (red). Researchers at Washington University School of Medicine in St. Louis have found that improving the function of the network, known as the meningeal lymphatics, can make certain experimental Alzheimer’s therapies more effective in mice. (Image: Sandro Da Mesquita)
April 28, 2021 SHARE
Experimental Alzheimer’s drugs have shown little success in slowing declines in memory and thinking, leaving scientists searching for explanations. But new research in mice has shown that some investigational Alzheimer’s therapies are more effective when paired with a treatment geared toward improving drainage of fluid and debris from the brain, according to a study led by researchers at Washington University School of Medicine in St. Louis.
Major study confirms increased risk of death, serious illness among COVID-19 survivors Pregnant women with pandemic face high mortality rate, 11% of babies contracts virus from their mothers Babies of women infected with coronavirus more likely to be born preterm, researchers find WHO, UNICEF, Gavi highlight urgent need for renewed global commitment to improve vaccination access, uptake A recent study published in the journal Nature showed that COVID-19 pandemic has derailed the fight against other dangerous diseases such as tuberculosis, measles, polio, malaria and Human Immuno-deficiency Virus (HIV)/Acquired Immune Deficiency Syndrome (AIDS). According to the Nature, after India went into lockdown in March 2020, the number of new tuberculosis (TB) cases detected there each day dropped by an alarming 70 per cent in one month.
The drainage network in a mouse s brain is outlined in blue and green, and dotted with clumps of the Alzheimer s protein amyloid beta (red). Researchers at Washington University School of Medicine in St. Louis have found that improving the function of the network, known as the meningeal lymphatics, can make certain experimental Alzheimer s therapies more effective in mice. Credit: Sandro Da Mesquita Read Time:
Experimental Alzheimer s drugs have shown little success in slowing declines in memory and thinking, leaving scientists searching for explanations. But new research in mice has shown that some investigational Alzheimer s therapies are more effective when paired with a treatment geared toward improving drainage of fluid and debris from the brain, according to a study led by researchers at Washington University School of Medicine in St. Louis.