Giving chemotherapy in the morning can extend survival of glioblastoma patients
An aggressive type of brain cancer, glioblastoma has no cure. Patients survive an average of 15 months after diagnosis, with fewer than 10% of patients surviving longer than five years. While researchers are investigating potential new therapies via ongoing clinical trials, a new study from Washington University in St. Louis suggests that a minor adjustment to the current standard treatment -; giving chemotherapy in the morning rather than the evening -; could add a few months to patients survival.
The study appears online in the journal Neuro-Oncology Advances.
Average overall survival for all patients in the study was about 15 months after diagnosis. Those receiving the chemotherapy drug temozolomide in the morning had an average overall survival of about 17 months post diagnosis, compared with an average overall survival of about 13½ months for those taking the drug in the evening, a statistically
Poster on Celsion Corporation s (CLSN) Phase I/II OVATION 2 Study Presented at the Society of Gynecologic Oncology Virtual Annual Meeting on Women s Cancer streetinsider.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from streetinsider.com Daily Mail and Mail on Sunday newspapers.
Holmes
Virologist Autumn Holmes, PhD, a postdoctoral researcher at Washington University School of Medicine in St. Louis, has been named a Hanna H. Gray Fellow by the Howard Hughes Medical Institute (HHMI). The fellowship provides up to $1.4 million over eight years to outstanding early-career scientists. Its aim is to help those with the potential to solve major challenges in the life sciences make the transition to becoming principal investigators.
Holmes’ research focuses on finding new therapies for emerging infectious diseases such as chikungunya. Transmitted by mosquito bite, chikungunya virus causes debilitating, often chronic arthritis in people. While chikungunya is still mostly confined to tropical parts of the planet, the mosquito species that carry the virus are likely to expand their range over the next few decades due to climate change.
E-Mail
Children hospitalized with breathing problems due to a common viral lung infection are likely to get sicker and remain hospitalized if they have high levels of defective copies of the virus, according to a new study by researchers at Washington University School of Medicine in St. Louis.
The findings, published April 1 in
Nature Microbiology, could help doctors identify those patients at high risk of severe illness due to respiratory syncytial virus (RSV), the most common cause of pneumonia and bronchiolitis (inflammation of the small airways) in children under age 5. Every child has been infected by RSV at least once before the age of 3, said senior author Carolina B. López, PhD, a professor of molecular microbiology and a BJC Investigator. Some infants and small children will just develop a cold, but others end up hospitalized. We don t really know what determines whether a child will get really sick or not. So when babies are admitted to the hospital with RSV, do