Starving cancer cells of the energy they need to grow could one day provide an alternative to a commonly used chemotherapy drug without the risk of severe side effects, according to a new study.
Studying human cancer cells and mice, researchers report that a two-drug combination targeting a tumor’s energy sources could prove as effective and less toxic than methotrexate, a long-used chemotherapy drug often given in high doses to treat osteosarcoma, a bone cancer.
Osteosarcoma is the most common tumor of the bone in adults and children. It accounts for about 4% of all pediatric cancers and more than half of all pediatric bone cancers. Standard treatment for osteosarcoma includes surgery, radiation, and a cocktail of chemotherapy drugs including high-dose methotrexate, which can cause liver and kidney damage.
February 1, 2021
The common COVID-19 symptoms of loss of smell and taste have stuck around for months for some recovered patients.
SHOW TRANSCRIPT
Doctors are worried about a growing number of COVID-19 survivors who still don t have a sense of taste or smell.
It s a common symptom that for many goes away with the virus, but for others it has stuck around months later.
Researchers are still trying to figure out why it affects people differently.
A doctor with Washington University School of Medicine predicts there will be at least 1 million new cases of people with chronically diminished senses in the coming year.
The Florida Times-Union
4:20 p.m. | Only 38% of nursing home workers accepted COVID-19 vaccines, new data shows
While residents of nursing homes and their caregivers have been considered a top priority for COVID-19 vaccination, only 38% of nursing home staff accepted shots when they were offered, new data from the Centers for Disease Control and Prevention revealed Monday.
Anecdotal reports have been circulating for weeks that nursing home staff members were turning down vaccination offers, but these are the first national-level figures. These findings show we have a lot of work to do to increase confidence and also really understand the barriers to vaccination amongst this population, said Dr. Radhika Gharpure, lead author of the study and a member of the CDC’s Vaccine Task Force. | Read more
This One Thing Could Determine If Your COVID Case Is Severe or Not
By Lauren Gray of Best Life |
This One Thing Could Determine If Your COVID Case Is Severe or Not
SARS-CoV-2, the virus that causes COVID-19, has a reputation for being unpredictable. Patients may begin their infection with a relatively mild set of symptoms, only to find them rapidly escalating into dangerous new territories in the days or weeks that follow. Now, scientists are racing to study innovative ways to identify those patients who might suffer the worst COVID cases
before their symptoms become severe. One such study from the Washington University School of Medicine in St. Louis has found that there is indeed a simple way to predict which hospitalized patients are at risk of serious complications or death. Using a rapid blood test that measures mitochondrial DNA, the researchers were able to spot patients who would later face the most serious COVID cases in a group of 100 hospitalized patients. Read