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US coronavirus cases rising again, doubling over three weeks
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US virus cases are rising again, doubling over three weeks
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U S COVID-19 cases rising again, doubling over three weeks
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US coronavirus cases rising again, doubling over three weeks
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Novel monoclonal antibody could pave way for future COVID-19 treatments and vaccines
Researchers in the United States have shown that targeting the N-terminal domain (NTD) of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) viral spike protein could achieve broad neutralization of variants of concern.
The SARS-CoV-2 virus is the agent responsible for the ongoing coronavirus disease 2019 (COVID-19) pandemic, and the spike protein is the main structure the virus uses to bind to and infect host cells. This spike is the primary target of neutralizing antibodies following SARS-CoV-2 infection and, therefore, the focus of most vaccine design approaches.
The team – from Icahn School of Medicine at Mount Sinai in New York and Washington University School of Medicine in Missouri – says the findings could inform the design of next-generation vaccines that will protect against both currently circulating and newly emerging SARS-CoV-2 variants of concern.