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Understanding 21 CFR Part 11 and its application

19 July 2021 In this expert resource, produced by SelectScience in association with Cytiva, we explore the 21 CFR Part 11 regulations issued by the U.S. Food & Drug Administration (FDA) and outline the responsibility of GxP lab users to understand and interpret these guidelines and validate relevant processes to ensure compliance. Download 10,000+

LC-MS of intact therapeutic monoclonal antibodies using Agilent AdvanceBio RP-mAb

16 July 2021 In this application note, Agilent Technologies analyze multiple therapeutic monoclonal antibodies (mAbs), including an antibody drug conjugate (ADC), using AdvanceBio RP-mAb columns in an LC-MS method. This approach delivered fast analysis times and accurate mass determination of intact mAbs.  Download 10,000+

High-throughput and sensitive size exclusion chromatography (SEC) of biologics using Agilent AdvanceBio SEC Columns

16 July 2021 In this application note, Agilent Technologies demonstrates the use of shorter and narrower Agilent AdvanceBio SEC columns for fast, high-resolution, sensitive, and reproducible separation and quantitation of monoclonal antibodies (mABs) and antibody drug conjugate (ADC).  Download 10,000+

Intrinsic electrical characterization of two-dimensional transition metal dichalcogenides via scanning probe microscopy

15 July 2021 Suitable techniques to characterize the intrinsic physical and electrical properties of as-deposited 2D materials, are a key link between the quality of as-deposited 2D materials and the performance of 2D materials-based electronic devices. In this application note, Park Systems investigates the intrinsic electrical properties of as-deposited 2D TMDs, utilizing scanning probe microscopy (SPM).  Download 10,000+

Enabling drug synergy and drug dose response assays

14 July 2021 Developing assays to assess the effectiveness of drug combinations or different doses of single drugs in vitro is an increasingly important area of drug and anticancer therapy research. In developing high throughput assays, researchers face the double challenge of quickly dispensing both viable cells and drug combinations. In particular, the dispensing of two or more compounds to create a dose-response matrix can be both labour intensive and compound expensive. Download 10,000+

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