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HSS and LimaCorporate Partner to Open First Provider-Based Design and 3D Printing Center for Complex Joint Reconstruction Surgery
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Opioid Use Among Older Adults By Sharon Liao
Part of getting older means that you may deal with aches and pain. To treat pain, your doctor may prescribe an opioid. You’ll join a large group of older adults: As many as 9% of adults age 65 and older take an opioid for pain.
Opioids are one of the strongest kinds of pain relievers. They can be very effective, especially for severe pain, says Cary Reid, MD, PhD, an associate professor of medicine at Weill Cornell Medical College in New York and a pain management researcher.
But they also come with serious side effects, and older adults are at a greater risk. If they’re not taken as prescribed, opioids can lead to a dependence or even addiction. “As doctors, we’re constantly questioning if opioids do more good than harm,” Reid says.
In MS, the immune system targets nerve cell axons that transmit signals from the brain to other parts of the body, leading to inflammation and nerve degeneration.
Degeneration in certain nerve layers in the back of the eye appear to correlate with greater brain damage in MS. Thus, the neuroprotective effects of current MS therapies can be examined through their impact on these layers.
In this study, researchers at the University of Sydney, in Australia, examined the impact of several approved DMTs on retinal ganglion cell loss in MS patients.
To assess retinal nerve cell degeneration, they compared the thinning of three retina layers the global peripapillary retinal nerve fiber layer, the temporal retinal nerve fiber layer, and the ganglion cell inner plexiform layer over time in patients taking distinct DMTs.
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