ISU alumnus Jacobson named CEO of V Foundation for Cancer Research Wednesday, January 6, 2021 3:35 PM The V Foundation for Cancer Research, a top-rated cancer research charity, has named Shane Jacobson as its new chief executive officer. Jacobson, an Iowa State University alumnus and former vice president for development and alumni relations at Grinnell College, succeeds foundation CEO Susan Braun upon her retirement. Jacobson, most recently president and CEO of the University of Vermont Foundation, brings with him two decades of fundraising experience. “Combining his passion for sports and eradicating cancer, this new role will allow Jacobson to build upon the V Foundation’s tremendous growth over the past decade,” the organization said in a press release. Jacobson received his bachelor’s and master’s degrees from Iowa State University, and completed the Harvard University Management Development Program. At the University of Vermont, he le
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LOS ANGELES Scientists have long known that therapies that target the cancer-driving MAPK pathway are only effective in a handful of cancers with specific mutations in a cancer gene called BRAF, and these cancers that initially respond to the therapy often end up developing resistance to the treatment, resulting in relapse for many patients.
Now, scientists at the UCLA Jonsson Comprehensive Cancer Center describe a new combination therapy that suppresses the MAPK pathway by holding cancer-driving proteins in a death grip. This combination of two small molecules has the potential to treat not only BRAF mutated melanoma but also additional aggressive subtypes of cancers, including melanoma, lung, pancreatic and colon cancers that harbor common mutations in cancer genes called RAS or NF1.