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Hassles with child car seats linked to unsafe child passenger behaviors

 E-Mail Parents who reported more hassles using a child car seat or booster seat - such as the child is uncomfortable or having to make multiple trips in a day - were less likely to follow recommendations from the American Academy of Pediatrics (AAP) on child passenger safety, according to a study published in the journal Academic Pediatrics. Researchers obtained information about transportation safety behaviors and 20 hassles when using child car seats among 238 socioeconomically and racially diverse parents of children 1 to 10 years of age. Eighty percent of parents reported at least a little bit of a problem with one or more of the hassles. On average, parents had a problem with five of the hassles. Parents who were not following the AAP recommendations indicated the hassles were bigger problems.

Potential target for treating many cancers found within GLI1 gene

 E-Mail Scientists from the Stanley Manne Children s Research Institute at Ann & Robert H. Lurie Children s Hospital of Chicago found that a region within the DNA of the cancer-promoting GLI1 gene is directly responsible for regulating this gene s expression. These findings, published in the journal Stem Cells, imply that this region within GLI1 could potentially be targeted as cancer treatment, since turning off GLI1 would interrupt excessive cell division characteristic of cancer. From previous research, we know that GLI1 drives the unrelenting cell proliferation that is responsible for many cancers, and that this gene also stimulates its own expression, says co-senior author Philip Iannaccone, MD, PhD, Professor Emeritus at the Manne Research Institute at Lurie Children s and Northwestern University Feinberg School of Medicine. We established in living human embryonic stem cells that removing the GLI1 regulatory region eliminated GLI1 expression and halted its activity. Th

Increase in medicaid managed care for youth linked to slightly more preventive care

 E-Mail Youth enrollment in Medicaid managed care across all states increased from 65 percent in 2000 to 94 percent in 2017. Across the country, receipt of preventive care for youth in Medicaid managed care increased from 49 percent in 2000 to 59 percent in 2017, falling short of the 80 percent annual goal set by the Centers for Medicare and Medicaid Services (CMS). Receipt of preventive care for youth in Medicaid managed care showed a significant increase in 17 states, a significant drop in six states, and no change in 28 states. Tennessee had the largest increase in preventive care associated with Medicaid managed care, while North Carolina showed the largest decrease.

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