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Credit: Correspondence to - Ofer Isakov - oferis@tlvmc.gov.il
Effect of liver fibrosis on survival in patients with intrahepatic cholangiocarcinoma: a SEER population-based study which reported that the impact of fibrosis on overall and cancer-specific survival 12, 36, and 60 months following diagnosis, was evaluated in the entire cohort and in subgroups stratified according to treatment approach and the American Joint Committee on Cancer tumor stage using a Cox proportional-hazards model.
After adjusting for age, sex, race, year of diagnosis, AJCC stage, and surgical treatment strategy, advanced fibrosis was associated with worse cancer-specific survival across follow-up periods.
Similar effects were observed for overall survival.