SRINAGAR: In the just concluded World Medical Innovation Forum, the 12 medical emerging gene and cell therapy (GCT) that were featured included one piloted by Kashmir scientist, Dr Khalid Shah.
Which biopharma startups will compete at INVEST Pitch Perfect? medcitynews.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from medcitynews.com Daily Mail and Mail on Sunday newspapers.
Harvard researchers have identified a mechanism explaining how chronic stress may lead to hair loss, according to a study published in Nature last month.
Researchers at Harvard, MIT, Massachusetts General Hospital, Icahn School of Medicine at Mount Sinai in New York, and University Hospital Würzburg in Germany collaborated on the study, which was helmed by Ya-Chieh Hsu, a biology professor at Harvard and faculty member at the Harvard Stem Cell Institute.
The study found the stress hormone corticosterone inhibited hair follicle stem cell activity and hair growth in mice. The researchers reported that when corticosterone levels were low in mice, their hair follicle stem cells regenerated much more frequently. However, when corticosterone levels were high due to chronic stress, the hair follicles entered a dormant phase.
Share This
The FINANCIAL Harvard University researchers have identified the biological mechanism by which chronic stress impairs hair follicle stem cells, confirming long-standing observations that stress might lead to hair loss.
In a mouse study published in the journal Nature, the researchers found that a major stress hormone puts hair follicle stem cells into an extended resting phase, without regenerating the follicle or the hair. The researchers identified the specific cell type and molecule responsible for relaying the stress signal to the stem cells, and showed that this pathway can be potentially targeted to restore hair growth.
“My lab is interested in understanding how stress affects stem cell biology and tissue biology, spurred in part by the fact that everyone has a story to share about what happens to their skin and hair when they are stressed. I realized that as a skin stem cell biologist, I could not provide a satisfying answer regarding if stress indeed has