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Public talk from the start focused on the risk to public confidence of any shortcuts, any deviation from standard development protocols. The media took up the chant. Federal agencies and politicians had a natural incentive to minimize any blowback on themselves from departing from accepted models of drug development. But it’s not obvious this was optimal under conditions of the pandemic. To repeat, a finished vaccine design was on hand by late January. China’s and Russia’s governments are hardly models of transparency and accountability but their leaders are not without cost-benefit incentives. They launched large voluntary distributions of relatively less-tested vaccines. Some in the U.S. called for challenge trials, deliberately infecting volunteers with Covid-19, to speed development. Classic double-blind trials with a placebo arm are the gold standard. In the trade-off between speed and safety, silver and bronze approaches were always possible to get a vaccine into the mar

New yorkUnited statesNew jerseyHoward university hospitalDistrict of columbiaCharlie bakerDow jones company incGetty imagesWas hiding among coldsWest africa ebolaAll rightsபுதியது யார்க்ஒன்றுபட்டது மாநிலங்களில்புதியது ஜெர்சிஹோவர்ட் பல்கலைக்கழகம் மருத்துவமனைமாவட்டம் ஆஃப் கொலம்பியா