>> narrator: by the 1470s, the power families has been embroiled in power struggles for generations and the newly appointed pope sixtus iv feels an imminent threat from one of his rivals. >> there's conflict with the d medicis. >> they were a messy family. i think about them being the dynasty of the renaissance. >> narrator: the medicis has interfered with businesses of the de la rovaries. >> one of them says the answer to our problem is get rid of the medici, get rid of this headach