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A yes on California's Proposition 1 will amend the state's constitution to say that the state cannot take away a person's right to abortion or contraception and will not interfere with reproductive freedoms.
Incumbent Linda Gorton faces Lexington City councilman David Kloiber in a race to represent Lexington, Kentucky.
Democrat Kendra Horn, who flipped a House seat in 2018, runs a long-shot campaign against Trump-endorsed Markwayne Mullin in ruby-red Oklahoma.
Polls close in the state at 7 p.m. in the mountain time zone and 8 p.m. in the central time zone.
Trump-endorsed Katie Britt is strongly positioned to defeat her Democratic opponent Will Boyd to defend Alabama's deep-red seat.