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Forendo Pharma Successfully Completes Phase 1 Studies of FOR-6219 in Endometriosis, Aiming to Advance Program into Phase 2 Clinical Studies


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Forendo Pharma, a clinical-stage drug development company focusing on novel treatments in women's health, today announced the completion of Phase 1 studies in healthy volunteers for its lead development program in endometriosis, FOR-6219, and provided a development outlook. The successfully concluded Phase 1 program demonstrated that FOR-6219, a HSD17B1 enzyme-targeting small-molecule, was safe and well-tolerated and delivered additional results supporting Forendo's therapeutic concept. The company is now planning the Phase 2 program including endometriosis patients in the US.
"The now completed Phase 1 program delivered an initial body of tolerability, safety and pharmacokinetic data. For chronic endometriosis treatment, tolerability and a lack of systemic estrogen deficiency-related side effects are of the utmost importance as we see current therapies struggling to be widely adopted due to their side effect profiles. A local effect on the target tissue with our intracrinology mechanism provides an opportunity for superior management of endometriosis," commented Risto Lammintausta, CEO of Forendo. "We are now looking forward to expanding our clinical development program into the US and potentially into complementary women's health indications, in addition to endometriosis. The upcoming Phase 2 program will transition the clinical evaluation of FOR-6219 into symptomatic patients and deepen our understanding of the drug's impact on the disease biology and endometriotic tissue."

Finland , Kostenloser-wertpapierhandel , Forendo-pharma , Caroline-rufo , Risto-lammintausta , Linkedin , Twitter , Karolinska-development , Novartis-venture-fund , Novartis , Novo-seeds , Vesalius-biocapital

Detailed text transcripts for TV channel - FOXNEWS - 20150716:18:27:00

armed forces recruiting center. you would have had multiple services army navy and others national guard, at that shopping mall on lee highway, 6219 lee highway was the address. you have seen the pictures of the broken glass. the shots fired through the glass door of that recruiting center where the reports -- again, we can't confirm them from the pentagon but the reports from chattanooga suggest nobody was injured at the recruiting site but there were people inside the recruiting center. so again, we're awaiting the police press conference. the mayor had come out originally describing the scene as horrific. the shooting scene at these two locations. the u.s. navy can only confirm that there were shots fired at two separate locations seven and a half miles apart. >> jennifer griffin live at the pentagon as she awaits official word from the pentagon there. we are still awaiting a press conference to come out of chattanooga. the first one was supposed to be

Strip-mall-on-lee-highway , Navy , Center , Army , National-guard , Services , Armed-forces , Shopping-mall , Lee-highway-6219 , 6219 , Downtown-chattanooga , Recruiting-center

Detailed text transcripts for TV channel - FOXNEWS - 20150716:17:29:00

recruiters told him that they were not hurt that they had evacuated. he went on to say he had no more information for recruiters from other branches at the facility. as we're getting a little bit more information on this it looks like it's not just the one facility that perhaps it is now two facilities because that's what we've been hearing repeatedly all morning long. >> the navy is confirming that shots were fired at two separate facilities involving naval personnel. about eight miles apart. one on abnacola highway, the naval reserve operations center there, and also the naval recruiting center at 6219 lee highway. the director at military personnel. >> we just got new information confirmed by authorities on victims. we now know there are five victims. we know that four of those victims are military personnel. that's the only way they've been described to us. beyond that i cannot tell you.

Information , Facility , Recruiters , It-looks , Branches , One , Us-navy , Personnel , Shots , Facilities , Two , Lee-highway

Detailed text transcripts for TV channel - FOXNEWS - 20150716:17:40:00

that is not where the marines were reportedly injured. at the recruiting center -- the reason this is confusing is several services the national guard as well as the army reserves as well as marines are located at that strip mall mall location on lee highway. we've seen the video that shows the door to that recruiting center was shot up by bullets, multiple bullets. we've seen the shattered glass. that's at the strip mall at 6219 lee highway in chattanooga. so it seems right now we cannot confirm but there are reports of four marines injured at that amnacola location, shepherd. >> we're working on a map. there's a glass company there and a woman named marilyn hutchinson was there and witnessed everything that happened apparently at the

Recruiting-center , Reason , Marines , Services , Guard , Army-reserves , Strip-mall-location-on-lee-highway , Injured , Bullets , Video , Door , Glass

Detailed text transcripts for TV channel - FOXNEWS - 20150716:17:32:00

around chattanooga. 6219 lee highway. the amnacola highway naval reserves operations center attacked by what appears to be a lone gunman. it is said that the shooter is down and the threat to the people of chattanooga is over. >> as we continue to take in some live shots, this is the scene coming out of chattanooga, tennessee. although it's our understanding that active shooting is now over the investigation still very much in just its first stages. as we wanted to clarify to you, shep gave us that information that it's our understanding that there are some military personnel that are injured according to the report that we have received. we did by way of the associated press get word from the spokesman of the u.s. army recruiting center in fort knox kentucky that the army recruiters were able to get out and there were no injuries in that particular office but as we've been reporting the u.s. navy is saying there were shots

Shooter , Lee-highway , Gunman , Operations , Amnacola-highway-naval , 6219 , Chattanooga-6219-lee-highway , Chattanooga , Scene , People , Threat , Shots