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Innovative Tool Pinpoints Infants High-Risk for RSV

Innovative Tool Pinpoints Infants High-Risk for RSV
miragenews.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from miragenews.com Daily Mail and Mail on Sunday newspapers.

United-states , Vanderbilt-university , Tennessee , American , Ferdinand-cacho , Brittney-snyder , International-conference , Vanderbilt-university-medical-center , Forum-infectious-diseases , Division-of-allergy , Tennessee-medicaid-program , Asthma-research

New tool helps identify babies at high risk for RSV

New tool helps identify babies at high risk for RSV
medicalxpress.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from medicalxpress.com Daily Mail and Mail on Sunday newspapers.

Tennessee , United-states , Vanderbilt-university , American , Brittney-snyder , Brittneym-snyder , Ferdinand-cacho , Vanderbilt-university-medical-center , Tennessee-medicaid-program , Division-of-allergy , Asthma-research , Centers-for-disease-control-prevention

Fibrosis-focused Endeavor bags $132.5M series C

Fibrosis-focused Endeavor bags $132.5M series C
fiercebiotech.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from fiercebiotech.com Daily Mail and Mail on Sunday newspapers.

United-states , American , John-hood , American-thoracic-society , Endeavor-biomedicines , Fierce-biotech , Matrix-capital-management , Symbiosis-capital-management , Velocity-capital ,

2024 Respiratory Health Award Recipients Announced

The American Thoracic Society has announced the awardees of the 2024 Respiratory Health Awards. All 15 awardees will be formally recognized as part of the ATS 2

Pune , Maharashtra , India , New-york , United-states , Mexico , San-diego , California , American , Edward-livingston-trudeau , Sonyek-danoff , Jeffreyl-curtis

Georgia man files lawsuit against Emory, others over race-based test for Black kidney transplant recipients

Georgia man files lawsuit against Emory, others over race-based test for Black kidney transplant recipients
atlantanewsfirst.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from atlantanewsfirst.com Daily Mail and Mail on Sunday newspapers.

Atlanta , Georgia , United-states , University-hospital , Americans , American , Cleveland-holt , United-network-for-organ , United-network-for-organ-sharing , American-heart-association , American-society-of-nephrology , Duke-university-health-system

How Working Conditions in Civilian Jobs Can Affect Veterans' Health and Well-Being

How Working Conditions in Civilian Jobs Can Affect Veterans' Health and Well-Being
rand.org - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from rand.org Daily Mail and Mail on Sunday newspapers.

United-states , Iraq , White-house , District-of-columbia , Iraqi , American , Americans , Danielj-epstein , Joe-biden , Heath-robinson , Us-census-bureau , Us-department-of-defense

Necroptosis blockade prevents lung injury in severe influenza

Severe influenza A virus (IAV) infections can result in hyper-inflammation, lung injury and acute respiratory distress syndrome1–5 (ARDS), for which there are no effective pharmacological therapies. Necroptosis is an attractive entry point for therapeutic intervention in ARDS and related inflammatory conditions because it drives pathogenic lung inflammation and lethality during severe IAV infection6–8 and can potentially be targeted by receptor interacting protein kinase 3 (RIPK3) inhibitors. Here we show that a newly developed RIPK3 inhibitor, UH15-38, potently and selectively blocked IAV-triggered necroptosis in alveolar epithelial cells in vivo. UH15-38 ameliorated lung inflammation and prevented mortality following infection with laboratory-adapted and pandemic strains of IAV, without compromising antiviral adaptive immune responses or impeding viral clearance. UH15-38 displayed robust therapeutic efficacy even when administered late in the course of infection, suggesting that RIPK3 blockade may provide clinical benefit in patients with IAV-driven ARDS and other hyper-inflammatory pathologies. A newly developed RIPK3 inhibitor blocks necroptosis of lung cells, reduces lung inflammation and prevents mortality in a mouse model of influenza A virus infection.

United-states , American , American-thoracic-society , Care-med , Host-microbe , Microbes-infect , Tissue-res , Death-dis , Cell-proteomics , Cancer-res , Cell-physiol