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Biotherapeutic regulatory filingsrequire detailed characterization of degradation pathways including aggregation. Learn how three orthogonal light scattering techniques complement each other to analyze and quantify soluble and sub-micron insoluble aggregates. This poster describes the capabilities of SEC-MALS, FFF-MALS and CG-MALS and how they work together to provide a comprehensive picture of irreversible and reversible aggregates.

Oncology drug discovery capabilities Geaneth Martins Zeni, laboratório central prefeitura de vitória ES Jason Wong, Anresco Laboratories Fnu Adnan, University of Swat Tanya Singh, Cardiff University Help over Be the first to review brand new products help shape new technologies June 13 May 2021 In this application note, explore how Charles River can support every phase of oncology drug discovery and development, from target identification to IND. Download 10,000+

Fast and automated TSA-based multiplexed immunofluorescence Geaneth Martins Zeni, laboratório central prefeitura de vitória ES Jason Wong, Anresco Laboratories Fnu Adnan, University of Swat Tanya Singh, Cardiff University Help over Be the first to review brand new products help shape new technologies June 13 May 2021 TSA-based multiplexing is a precise tool in immunostaining to unravel the complexity of the tumor microenvironment. This application note presents a rapid and automated high-plex ...

The Ionic system produces more higher quality nucleic acid due to less fragmentation and no risk of contamination from wash buffers or beads. When higher quality material is input into downstream analysis, superior results can be obtained; providing more biological insight for researchers or more robust and reliable results for clinicians.

Simultaneous extraction and purification of both RNA and DNA from FFPE tissue samples is critical to enable multiple downstream analyses from rare or limited samples. To avoid yield loss, most technologies use a serial isolation approach where DNA and RNA are separated after lysis by filtration or precipitation before entering separate purification workflows. This results in twice the number of purification steps per sample.  With simultaneous extraction and