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Smartlink Holdings, Tejas Networks, Sudarshan Chemical, Cochin Shipyard and Indraprastha Med, hit their fresh 52-week highs during the day.
Sun Pharma, Tata Consumer, BPCL, Coal India Ltd and Hindalco were among the top losers on NSE.
In the Nifty pack, 30 stocks were trading in the green, while 20 stocks were trading in the red.
The Nifty Realty index closed 2.58 per cent up at 957.2.
The Nifty Pharma index closed 0.96 per cent down at 18463.75.