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Designer SARS-CoV-2 RBD vaccine produces dramatically improved antibody response in preclinical trials


Designer SARS-CoV-2 RBD vaccine produces dramatically improved antibody response in preclinical trials
The importance of computational modeling in the prediction of the course of the ongoing coronavirus disease 2019 (COVID-19) pandemic, as well as evaluating multiple potential drug leads, has never been more clear. Now, a new study describes a set of designer vaccine antigens that may improve vaccine stability as well as enhance the neutralizing antibody response.
The virus causing this pandemic is the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which causes an asymptomatic or mild infection in the vast majority, but spreads rapidly and extensively to produce a huge caseload in a relatively short period of time. This has led to overwhelming demands on healthcare services in many severely affected countries. ....

South Africa , South African , Liji Thomas , Protein Expression , Epitope Design , Coronavirus Disease Covid 19 , Ars Cov 2 , Spike Protein , Amino Acid , Computational Modeling , Evere Acute Respiratory , Evere Acute Respiratory Syndrome , ப்ரோடீந் வெளிப்பாடு ,

Computational Modeling in Medicine


Computational Modeling in Medicine
In the past few decades, information technology has revolutionized the medical industry. The accuracy with which biological systems and interactions can be simulated and data can be gathered have improved exponentially. Computational modeling has provided ever-more sophisticated data for the field of medical research. This article will discuss this subject.
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What is computational modeling?
Computational modeling is used to simulate and study complex systems using computer science, physics, and mathematics. Numerous variables are programmed into the computational model to characterize the system which is being studied. By adjusting these variables alone or in various combinations, the outcome can be observed, providing valuable data for researchers. ....

United States , Alberto Figueroa , Alvaro Mata , Neelanjana Sengupta Tedxhitkolkata , Nature Communications , Drug Administration Staff , University Of Michigan , Computational Biology , Neelanjana Sengupta , Computational Modeling Studies , Medical Device Submissions , Industry Food , Digital Twin , European Hart Journal , Computational Modeling , ஒன்றுபட்டது மாநிலங்களில் , ஆல்பர்டோ ஃபிகேரோவ , அல்வாரோ மாதா , இயற்கை தகவல்தொடர்புகள் , பல்கலைக்கழகம் ஆஃப் மிச்சிகன் , கணக்கீட்டு உயிரியல் , மருத்துவ சாதனம் சமர்ப்பிப்புகள் , டிஜிட்டல் இரட்டை , கணக்கீட்டு மாடலிங் ,