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>> announcer: this is “nbc nightly news” with lester holt good evening, everyone we're getting a much fuller picture of the apparent plot, the frightening near-miss for another community, and the heartbreaking depth of loss following the july 4th attack on parade goers in highland park, illinois today, the state's attorney there saying the 21-year-old now charged in the murders of seven people has confessed and that he went into details about what he had done officials revealing that after the highland park shootings, robert crimo iii considered unleashing a second attack 2 1/2...

the showdown in the courtroom. the coldest blast of the season so far from texas to the northeast. we're tracking it. the delta pilot charged with pulling a gun in the cockpit why authorities say he threatened to shoot the captain midflight. and the marathon man running on the road to redemption >> announcer: this is "nbc nightly news" with lester holt good evening, and welcome. a diplomatic breakthrough has cracked open the door that has left foreigners, including americans, trapped inside war-torn gaza tonight, americans are among a handful of people who were able to leave ...

>> announcer: this is "nbc nightly news" with lester holt good evening in the constant chase to get ahead of covid-19, a new omicron-specific vaccine is about to enter testing but in a measure of just how quickly this pandemic is evolving, the question being asked, will we need it by the time it's ready? the modified vaccine by pfizer perhaps months away as new covid cases continue to drop, still leaving overwhelmed hospitals, which are now finding some antibody treatments against omicron are not working. also today, the biden administration is pulling its rule that employees at large comp...

Officials tell nbc news they are concerned russia could potentially be preparing to use chemical or biological weapons in ukraine richard engel is far to the east of me in kyiv and starts our coverage >> reporter: vladimir putin says russians should be proud of what their soldiers are doing in ukraine, but where's the honor in bombing a children's and maternity hospital in a city that's surrounded? no patients were reported killed in this attack, but pregnant women were among those who were helped out of the building ukraine called it a war crime and says children are still trapped. >> i canno...

Sales, it is giving tuesday. how you can give back this holiday season. this is "nbc nightly news" with lester holt. >> good evening. discouraging words tonight from the head of vaccine maker moderna, quoted as saying there could be a material drop in the effectiveness of current vaccines against the omicron variant. while late today pfizer filed for approval of booster shots for 16 and 17-year-olds, hoping to protect as many people as possible scientists are feverishly trying to understand the heavily mutated variant, now tracing its origins to a different and earlier path than first though...