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Frontiers | Systems Immunology Analysis Reveals the Contribution of Pulmonary and Extrapulmonary Tissues to the Immunopathogenesis of Severe COVID-19 Patients


2Luebeck Institute of Experimental Dermatology, University of Luebeck, Luebeck, Germany
3General Surgery Department, Tawam Hospital, SEHA, Al Ain, United Arab Emirates
4Center for Biotechnology, Khalifa University of Science and Technology, Abu Dhabi, United Arab Emirates
5Department of Genetics and Molecular Biology, Khalifa University of Science and Technology, Abu Dhabi, United Arab Emirates
6Department of Respiratory Medicine, Rashid Hospital, Dubai Health Authority, Dubai, United Arab Emirates
7Meakins-Christie Laboratories, McGill University, Montreal, QC, Canada
8Division of Surgery and Interventional Science, University College London, London, United Kingdom
As one of the current global health conundrums, COVID-19 pandemic caused a dramatic increase of cases exceeding 79 million and 1.7 million deaths worldwide. Severe presentation of COVID-19 is characterized by cytokine storm and chronic inflammation resulting in multi-organ dysfunction. Curre ....

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