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Applegate says she has multiple sclerosis and described her condition as "a tough road." applegate first gained fame in the tv sitcom "married... with children." m.s. affects the nervous system and often leads to cognitive and physical decline. in 2008, applegate was diagnosed with breast cancer and underwent a double masectomy. and tonight we are remembering walter yetnikoff. he ran cbs records for many years when its superstar roster including billy joel, the rolling stones, and michael jackson. yetnikoff died sunday night, just shy of his 88th birthday. up next, a 12-year-old with an impres...

Increased risk of breast cancer. now, you might recall jolie revealed that she had undergone a double masectomy because the mutation put her at higher risk of the disease. today the high court ruled that human genes cannot be patented. i want to bring in jeffrey toobin to talk about that angle and the chief medical correspondent dr. sanjay gupta. jeff, i want to start with you first here. this particularly involves a case with a company that identified the brak a1 brca 2 jean mutation. what did the court decide. >> what the court said unanimously in an opinion written by just clarence thomas, ...

Decision i would say for jolie to publicly reveal such a private part of her life. she did not have breast cancer but chose to undergo a preventive double masectomy after she discovered she has the mutated brca 1 gene. that greatly increases her risk for breast aovarian cancers. it prompted a lot of questions. there are a couple of things i think worth pointing out. only less than 1% of all women actually carry the brca 1 or brca 2 jeans. out of the thousands diagnosed every year, only 5 to 10% of those patients have the defective gene. for someone like jolie with a strong family history of br...