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ASH 2023: Equity, Sickle Cell, and Real-Life Outcomes

Health equity, sickle cell disease, and the thoughtful use of artificial intelligence and social media are among the key themes to be presented at the annual meeting of the American Society of Hematology.

United-states , San-diego , California , Canada , Americans , American , Roberta-brodsky , Mikkaela-sekeres , Cynthiae-dunbar , National-heart , American-society-of-hematology

New Tools Available to Help Diagnose Skin Cancer

Emerging technologies aim to improve skin cancer diagnosis without biopsies.

Garden-city , New-york , United-states , Jonathan-ungar , Theodore-james-daly , Skin-cancer-center-at-mount-sinai , Drug-administration , Icahn-school , Mount-sinai-hospital , Mount-sinai-winter-symposium , Surgical-dermatology , Waldman-melanoma

SABCS 2023 Highlights Breast Cancer De-Escalation

From humble beginnings in 1977, 10,000 people are expected to attend this year's breast cancer meeting in San Antonio.

San-antonio , Texas , United-states , American , University-of-texas-health-san-antonio , American-association-for-cancer-research , Ut-health-san-antonio , San-antonio-breast-cancer-symposium , Virginia-kaklamani , Texas-health-san , Medscape-medical

Promising First Results With DNA Editing to Lower LDL

The first-in-human HEART-1 trial of in vivo DNA editing called VERVE-101, shows reductions in LDL and PCSK9 protein in patients with familial hypercholesterolemia.

Philadelphia , Pennsylvania , United-states , American , Andrew-bellinger , Karol-watson , Amgen , Novartis , American-heart-association , Verve-therapeutics , American-heart , Lipids

Placental Cell Disruption Tied to Adult Depression, CVD

Disruption of placental Hofbauer cell function caused by prenatal infection or preterm birth may increase the risk for depression and cardiovascular disease in adulthood.

Montreal , Quebec , Canada , New-york , United-states , Eamon-fitzgerald , Deepakl-bhatt , Nature-communications , Icahn-school-of-medicine-at-mount-sinai , Mcgill-university , Medscape-medical , United-kingdom-biobank

Are We Ready for Systematic Newborn Genome Sequencing?

Routine sampling and analysis of newborn DNA would enable screening for hundreds of childhood genetic diseases, but also raises concerns about privacy and ethics.

Italy , Belgium , Philadelphia , Pennsylvania , United-states , Boston , Massachusetts , New-york , United-kingdom , Paris , France-general- , France

Differences in Twins Suggest Obesity Veers From Genetics

When twins have significant differences in body mass index, the higher BMI more commonly veers from the genetically predicted BMI.

Finland , Helsinki , Eteläuomen-läi , Finnish , Bramj-berntzen , University-of-helsinki , Institute-for-molecular-medicine-finland , Older-finnish-twin-cohort , Molecular-medicine-finland , Obesity , Bese

Novel Blood Test Can Detect Rheumatoid Arthritis

An experimental assay detects epigenetic features within the unique patterns and sizes of cell-free DNA found in blood, but is it better than clinical diagnostics?

Fresenius-kabi , Kevinw-byram , Peter-taylor , Pfizer , University-of-oxford-england , Glaxosmithkline , American-college-of-rheumatology , Vanderbilt-university , American-college , Nordic-pharma , Rheumatoid-arthritis , A

FDA OKs First-Line Pembro With Chemo for Gastric/GEJ Cancer

Adding pembrolizumab to chemotherapy had significant benefits in patients with locally advanced unresectable or metastatic, HER2-negative gastric or gastroesophageal junction adenocarcinoma.

Drug-administration , Noncolorectal-gastrointestinal-cancer , Oncolorectal-gi-cancer , Chemotherapy , Combination-chemotherapy , Adenocarcinoma-gastroesophageal-junction- , Adenocarcinoma , Cancer , Alignant-neoplasia , Arcinoma , Gastric-cancer

Early Breast Cancer Detection From Breast Milk

Scientists in Spain have detected circulating tumor DNA in breast milk even before it appeared in blood.

Barcelona , Comunidad-autonoma-de-cataluna , Spain , Hebron , Israel-general- , Israel , Cristina-saura , Hebron-university-hospital , Hebron-institute-of-oncology , Cancer-genomics-group , Breast-cancer-group , University-hospital