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New Data Question Beta-Blockers Post-MI With Preserved EF

In patients who had revascularization after an acute MI and had a preserved EF, long-term beta-blocker use showed no benefit compared with no beta-blockers, in REDUCE-AMI.

Estonia , Sweden , Virginia , United-states , New-zealand , Wayne-batchelor , Troels-yndigegn , Vascular-institute-in-fairfax , University-hospital-in-lund , Interventional-council , American-college-of-cardiology , American-college

No Net HF Benefit for Interarterial Shunt Device

For an all-comer population with any impairment of LV function, an interarterial shunt device missed the primary endpoint in RELIEVE-HF, but benefit was seen with LVEF less than 40%.

Indiana , United-states , New-york , Massachusetts , Boston , Maryn-walsh , Patrickt-ogara , Icahn-school-of-medicine-at-mount-sinai , American-college-of-cardiology , Right-chamber-overload-might-explain-harm , Icahn-school

Clinical Trial Outcomes for Cardiac Myosin Inhibitors in oHCM Treatment

An expert in cardiology shares clinical trial findings of emerging and approved cardiac myosin inhibitors for the treatment of oHCM.

Jamesl-januzzi , Clinical-trial-outcomes , Cardiac-myosin-inhibitors , Ohcm-treatment , Obstructive-hypertrophic-cardiomyopathy , Peak-v02 , Safety , Ejection-fraction , Good-monitoring , Explorer-hcm , Valor-hcm

Who Benefits From Beta Blocker Withdrawal in HFpEF?

A new study suggested indexed left ventricular systolic volume may predict benefit of beta blocker withdrawal in patients with heart failure with preserved ejection fraction.

Spain , Valencia , Carabobo , Venezuela , Palau , University-of-valencia , Patricia-palau , Heart-failure , Cardiovascular-imaging , Ardiac-imaging , V-imaging

AVROBIO and Tectonic Therapeutic Announce Merger

Combined company to be Nasdaq-listed, clinical-stage biopharmaceutical company focused on advancing Tectonic’s novel GPCR-targeted therapeutic proteins

$130.7 million in private financing...

Erik-ostrowski , Timothya-springer , Houlihan-lokey , Piper-sandler , Tim-springer , Andrew-kruse , Andrewc-kruse , Alise-reicin , Goodwin-procter , Tectonic-therapeutic-inc , Nasdaq

AVROBIO Inc. (AVRO) and Tectonic Therapeutic Announce Merger

AVROBIO Inc. (AVRO) and Tectonic Therapeutic Announce Merger
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Alise-reicin , Houlihan-lokey , Erik-ostrowski , Piper-sandler , Andrewc-kruse , Timothya-springer , Nasdaq , Tectonic-therapeutic-inc , Avrobio-inc , Harvard-medical-school , Goodwin-procter

Positive Topline Results for SEQUOIA-HCM Trial in OHCM

Preliminary results of the pivotal phase 3 trial show benefit of the cardiac myosin inhibitor, aficamten, in obstructive hypertrophic cardiomyopathy.

China , Burlington , Massachusetts , United-states , Fadyi-malik , Martins-maron , Tufts-university-school-of-medicine , Drug-administration , Research-development , National-principal-investigator , National-medical-products-administration

FDA Expands Label for CVRx Barostim System in HF

The Barostim neuromodulation system is now indicated in NYHA class III or class II HF despite guideline-directed medical therapies, with LVEF ≤ 35% and NT-proBNP < 1600 pg/mL.

Nadim-yared , Drug-administration , Cvrx-inc , York-heart-association , New-york-heart-association , Heart-failure , Cardiovascular-imaging , Ardiac-imaging , V-imaging , Neurostimulation , Ejection-fraction , F-ejection-fraction

Study to Examine Routine ICD Implantation Post Heart Attack

The emergence of new medicinal treatments may have changed the risk-benefit ratio of routine ICD implantation in patients with a severely abnormal LVEF after a heart attack.

Czech-republic , Denmark , United-kingdom , Sweden , Israel , Spain , Belgium , Germany , Poland , France , Hungary , Austria

Clinical Trial Results from Peerbridge Health Unveil Direct-from-ECG Sleep Apnea Detection Using COR Wearable Platform

Peerbridge Health has announced the successful completion and findings of its prospective, feasibility clinical trial, resulting in a statistically significant 91.2% predictive accuracy for the determination of apnea-hypopnea index (AHI) for diagnosing obstructive sleep apnea (OSA) while using the Peerbridge Cor, a patented 3-lead, 2-channel wireless continuous ECG wearable device that allows physicians the ability to address and assess sleep and heart health remotely.

Texas , United-states , Northwell , American , Americans , Andrea-natale , Chris-darland , Nicholas-skipitaris , American-academy-of-sleep-medicine , David-medical-center , Northwell-health , Peerbridge-health