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Speculation about that woman in the firm who'd been killed. >> whether melissa knew about the ponzi scheme is one of those great mysteries. >> reporter: scott had started his ponzi scheme three years before melissa was murdered. >> is it time to take a fresh look at the whole melissa lewis murder? is there something more sinister? >> reporter: detective brian kendall now had a whole new problem with his fairly straightforward case against tony, the jealous train engineer. is this woman, melissa, killed because she knew too much? >> after we think we had this solid, buttoned-up case, "we do hav...

2010, he was sentenced to 50 years in prison. but one big question emerged, speculation about that woman in the firm who'd been killed. >> whether melissa knew about the ponzi scheme is one of those great mysteries. >> reporter: scott had started his ponzi scheme three years before melissa was murdered. >> is it time to take a fresh look at the whole melissa lewis murder? is there something more sinister? >> reporter: detective brian kendall now had a whole new problem with his fairly straightforward case against tony, the jealous train engineer. is this woman, melissa, killed because she knew...

Ponzi scheme comes into play?" >> reporter: the f.b.i. combed through the detectives files looking into a melissa-rothstein-ponzi link. >> they spent a week going through every inch of that case to find out if there was a connection to scott rothstein. >> reporter: with all these messy complications, tony's defense attorney, bruce fleisher, thought about two words, reasonable doubt. >> a lot of people thought that because of the rothstein ponzi scheme, that he had something to do with the murder of melissa lewis. >> reporter: and debra villegas was back in the hot seat herself, being grilled b...