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New system personalizes chemotherapy doses for cancer patients

When cancer patients undergo chemotherapy, the dose of most drugs is calculated based on the patient's body surface area. This is estimated by plugging the patient's height and weight into an equation, dating to 1916, that was formulated from data on just nine patients.

Giovanni-traverso , Nikhilb-lal , Louis-deridder , Jacquelinen-chu , Christopherm-colangelo , Robert-langer , Johanneslp-kuosmanen , Shriyas-srinivasan , Makaya-chilekwa , David-trumper , Josh-jenkins , Brianm-wolpin

CN Bio raises $21 million USD in first close of Series B investment round

Bayland Capital and founding shareholder, CN Innovations Holdings Ltd, to invest $10 M and $5.5 M, respectively. Investment will expand product development and scaling of the organization to meet increased demand for Organ-on-a-Chip (OOC) solutions.

United-kingdom , Cn-innovations-holdings-ltd , Holdings-ltd , Image-credit , Bayland-capital , Paul-brooks , Biopharmaceutical , Hip , Ompound , Rug-discovery , Fficacy

Investigating the efficacy and safety of existing drugs in patients with rare immune diseases

This month the first study within the DRIMID consortium (DRIMID stands for Drug Rediscovery for Rare Immune Mediated Inflammatory Diseases) has started.

Utrecht , Netherlands , Amsterdam , Noord-holland , Laar , Limburg , Rotterdam , Zuid-holland , Holland , Dutch , Radboudumc-nijmegen , Arthritis-research

Cruciferous vegetables may offer new hope for inflammatory bowel disease management

Study evaluates the role of cruciferous vegetables and their bioactive components in mitigating inflammatory bowel disease through in vitro, in vivo, and preliminary clinical investigations, suggesting a promising therapeutic avenue.

Brussels , Bruxelles-capitale , Belgium , United-states , America , Current-developments , Inflammatory-bowel , Image-credit , Ulcerative-colitis , North-america , Tumor-necrosis-factor

Korean fermented food Doenjang shows promise in alleviating menopausal symptoms

Study compares the effects of traditional versus commercial Korean Doenjang on menopausal symptoms, finding that traditional variants with high beneficial microorganisms are more effective in reducing these symptoms and improving cardiovascular and gut health.

Food , Nxiety , Acteria , Lood , Reast-cancer , Ancer , Ardiovascular-disease , Holesterol , Linical-trial , Fficacy , Strogen

Metabolic health determines effectiveness of influenza vaccination

Metabolic health (normal blood pressure, blood sugar and cholesterol levels, among other factors) influences the effectiveness of influenza vaccinations. Vaccination is known to be less effective in people with obesity compared to those with a healthier body mass index (BMI), but St. Jude Children's Research Hospital scientists have found it is not obesity itself, but instead metabolic dysfunction, which makes the difference.

Vermont , United-states , Alexandra-mandarano , Ericka-kirkpatrick-roubidoux , Pamela-brigleb , Brandi-livingston , Benjamin-wilander , Paul-thomas , Stacey-schultz , Maureen-mcgargill , R-chris-skinner , Rebekah-honce

New sleep-enhancing nutraceutical blend falls short in clinical trial

Study investigates the impact of a unique nutraceutical blend, combining L-theanine with valerian, saffron, and lemon balm extracts, on improving sleep quality, finding no significant difference compared to a placebo in individuals experiencing poor sleep.

Colombia , Bogota , Cundinamarca , Asso-shutterstock , Scientific-reports , Nutraceutical , Leep , Lood , Hronic , Iet , Fficacy

Study unlocks how cortisone activates the body's natural "brakes" on inflammation

Cortisone and other related glucocorticoids are extremely effective at curbing excessive immune reactions.

Berlin , Germany , Uniklinikum-erlangen , Department-of-rheumatology , Ulm-university , Department-of-medicine , Clinical-immunology , Jean-philippe-auger , Anti-inflammatory , Lood , Lood-pressure , Ell

Annual COVID-19 vaccine proves to be a wise investment for personal health and pocketbook

Study finds that receiving an annual COVID-19 vaccine is clinically and economically beneficial for individuals, regardless of insurance status, offering savings by reducing the likelihood of infection and its associated costs.

United-states , Infectious-diseases , Image-credit , Coronavirus-disease-covid-19 , Accine , Oronavirus , Fficacy , Ealth-insurance , Nfectious-diseases , Ortality , Espiratory

Three early-phase clinical studies show promising initial data for patients with lymphoma, gastric cancers

Three early-phase clinical studies presented by researchers from The University of Texas MD Anderson Cancer Center at the American Association for Cancer Research (AACR) Annual Meeting 2024 show promising initial data for patients with lymphoma, gastric or gastroesophageal junction cancers, and specific molecularly selected tumors.

United-states , Texas , American , Klus-pharma , Jordi-rodon , Timothy-yap , Merck-co , Development-agreement , Andrew-sabin-family-fellowship-program , American-association-for-cancer-research , University-of-texas-md-anderson-cancer-center , Experimental-therapeutics-clinical-trials-network