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Found the front gate locked. when he peered over the fence, he saw his wife's body. >> roger was in total shock. and he first called gen-probe. he didn't call the police. he called gen-probe. that shows how disoriented he was. >> the crime scene appeared to be staged. it had the earmarks of a robbery, but no money was missing from helena's wallet. >> you had her purse that was strewn about. they preserved all of that for fingerprints or other evidence, of which, unfortunately, there were none. >> there was no physical evidence left. obviously, he wore gloves. i mean, one safely can assume that...

For 13 years, the murder of bio-tech research scientist helena greenwood went unsolved. the medical examiner found what looked to be blood under one of her fingernails. at the time, it was far too small for dna analysis. by 1998, however, work that gen-probe and scientists like helena greenwood had been working on led to new developments in dna testing. one of the most important was polymerase chain reaction or pcr which enabled scientists to copy minute dna samples until they were large enough to test. >> polymerase chain reaction allows you to make dramatically

Greenwood and they knew it was david paul frediani, but they couldn't prove it. >> eventually helena greenwood's murder was relegated to san diego's cold case files and forgotten. over the next several years, helena's parents died, her husband, roger, developed cancer and he, too, passed away. >> and who is there to mourn for helena? very few and growing fewer. >> and gen-probe went about the work helena had been pursuing before her death, looking for ways to use new dna technology for quicker, faster medical diagnoses. david frediani served only three years of his five-year sentence and was r...