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'Good cholesterol' may protect liver – Washington University School of Medicine in St. Louis

Brad W. Warner
A new study from Washington University School of Medicine in St. Louis shows that a type of good cholesterol called HDL3, when produced in the intestine, protects the liver from inflammation and injury. First author Yong-Hyun Han, PhD, (left) and co-author and Washington University surgical resident Emily Onufer, MD, work in the surgical suite where the mouse surgeries were conducted as part of this study. Han did this work while a postdoctoral researcher in the lab of senior author Gwendalyn Randolph, PhD.
The body’s so-called good cholesterol may be even better than we realize. New research from Washington University School of Medicine in St. Louis suggests that one type of high-density lipoprotein (HDL) has a previously unknown role in protecting the liver from injury. This HDL protects the liver by blocking inflammatory signals produced by common gut bacteria. ....

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These bacteria-gobbling immune cells help the body heal—but also cause surgical complications

These bacteria-gobbling immune cells help the body heal—but also cause surgical complications
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Scientists to explore whether anti-inflammatory drugs control blood sugar

Date Time
Scientists to explore whether anti-inflammatory drugs control blood sugar
Meals prepared for scientific studies of metabolism and nutrition stand ready for distribution at Washington University School of Medicine in St. Louis. Researchers at the School of Medicine are studying whether drugs to treat inflammatory conditions such as Crohn’s disease also could help control blood sugar levels. (Photo: Matt Miller/School of Medicine)
Inflammation and metabolic disorders are deeply intertwined. For example, people with inflammatory conditions such as Crohn’s disease and psoriasis are at risk of developing metabolic disorders such as insulin resistance and diabetes. However troubling that connection might seem, it also might point to some promising news. ....

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